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Scientific publications of the clinical lipidomics unit

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    • Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid AccumulationBiomedicines2022-06-03 | journal-articleSource:Crossref
    • Lipidomics Reveals Cisplatin-Induced Renal Lipid Alterations during Acute Kidney Injury and Their Attenuation by CilastatinInternational Journal of Molecular Sciences2021-11-20 | journal-articleSource:Crossref
    • A normalized signal calibration with a long-term reference improves the robustness of RPLC-MRM/MS lipidomics in plasmaAnalytical and Bioanalytical Chemistry2021-06-28 | journal-articleSource:Crossref
    • The Antipsychotic Risperidone Alters Dihydroceramide and Ceramide Composition and Plasma Membrane Function in Leukocytes In Vitro and In VivoInternational Journal of Molecular Sciences2021-04-10 | journal-articleSource:Crossref
    • Long-term docosahexaenoic acid (DHA) supplementation in cystic fibrosis patients: a randomized, multi-center, double-blind, placebo-controlled trial.Prostaglandins, leukotrienes, and essential fatty acids2020-10 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • One-year dietary supplementation with walnuts modifies exosomal miRNA in elderly subjects.European journal of nutrition2020-09-26 | journal-articleSource:OSCAR PASTOR
    • Hepatic Synaptotagmin 1 is involved in the remodelling of liver plasma- membrane lipid composition and gene expression in male Apoe-deficient mice consuming a Western diet.Biochimica et biophysica acta. Molecular and cell biology of lipids2020-08-07 | journal-articleSource:OSCAR PASTOR
    • Non-selective beta-blockers impair global circulatory homeostasis and renal function in cirrhotic patients with refractory ascites.Journal of Hepatology2020-05-21 | journal-articleSource:OSCAR PASTOR
    • Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis.Biochimica et biophysica acta. Molecular and cell biology of lipids2020-01-25 | journal-articleSource:OSCAR PASTOR
    • Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease.Scientific reports2019-09-06 | journal-articleSource:OSCAR PASTOR
    • Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy.Frontiers in neuroscience2019-04-24 | journal-articleSource:OSCAR PASTOR
    • Intestinal Immune Dysregulation Driven by Dysbiosis Promotes Barrier Disruption and Bacterial Translocation in Rats With Cirrhosis.Hepatology (Baltimore, Md.)2019-03-05 | journal-articleSource:OSCAR PASTOR
    • A Pilot Study of Serum Sphingomyelin Dynamics in Subjects with Severe Obesity and Non-alcoholic Steatohepatitis after Sleeve Gastrectomy.Obesity surgery2018-11 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • A comprehensive evaluation of omega-3 fatty acid supplementation in cystic fibrosis patients using lipidomics.The Journal of nutritional biochemistry2018-10-11 | journal-articleSource:OSCAR PASTOR
    • Differential effects of restrictive and malabsorptive bariatric surgery procedures on the serum lipidome in obese subjectsJournal of Clinical Lipidology2018-07 | journal-articleSource:Crossref
    • Ellagic acid protects from myelin-associated sphingolipid loss in experimental autoimmune encephalomyelitis.Biochimica et biophysica acta2018-05 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • Hormone-sensitive lipase deficiency disturbs lipid composition of plasma membrane microdomains from mouse testis.2016-06 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport.2016 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • First-Generation Antipsychotic Haloperidol Alters the Functionality of the Late Endosomal/Lysosomal Compartment in Vitro.2016 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • Obeticholic acid reduces bacterial translocation, restores intestinal barrier and inhibits inflammation in cirrhotic rats.2015-12 | journal-articleSource:OSCAR PASTORviaEurope PubMed Central
    • Quantitative lipidomic analysis of plasma and plasma lipoproteins using MALDI-TOF mass spectrometry.2015-05 | journal-article
      • PMID: 26004846
      • DOI: 10.1016/j.chemphyslip.2015.05.005
      Source:OSCAR PASTORviaEurope PubMed Central
    • Effect of Infliximab in oxidised serum albumin levels during experimental colitis.2014-12 | journal-article
      • PMID: 25382460
      • DOI: 10.3109/1354750X.2014.982189
      Source:OSCAR PASTORviaEurope PubMed Central
    • Clinically used selective estrogen receptor modulators increase LDL receptor activity in primary human lymphocytes.2014-11 | journal-article
      • PMID: 25395200
      Source:OSCAR PASTORviaEurope PubMed Central
    • Curcumin promotes exosomes/microvesicles secretion that attenuates lysosomal cholesterol traffic impairment.2014-04 | journal-article
      • PMID: 24288129
      • DOI: 10.1002/mnfr.201300350
      Source:OSCAR PASTORviaEurope PubMed Central
    • White fish reduces cardiovascular risk factors in patients with metabolic syndrome: the WISH-CARE study, a multicenter randomized clinical trial.2014-03 | journal-article
      • PMID: 24462043
      • DOI: 10.1016/j.numecd.2013.09.018
      Source:OSCAR PASTORviaEurope PubMed Central
    • Quantitative profile of lipid classes in blood by normal phase chromatography with evaporative light scattering detector: application in the detection of lipid class abnormalities in liver cirrhosis.2013-06 | journal-article
      • PMID: 23481451
      • DOI: 10.1016/j.cca.2013.02.007
      Source:OSCAR PASTORviaEurope PubMed Central
    • Hormone-sensitive lipase deficiency disturbs the fatty acid composition of mouse testis.2013-03 | journal-article
      • PMID: 23369366
      • DOI: 10.1016/j.plefa.2012.12.005
      Source:OSCAR PASTORviaEurope PubMed Central
    • Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro.2013-02 | journal-article
      • PMID: 23175778
      • PMC: PMC3588861
      • DOI: 10.1194/jlr.M026948
      Source:OSCAR PASTORviaEurope PubMed Central
    • Ribavirin Maintenance Treatment Reduces Portal Pressure In Hepatitis C Virus Cirrhosis: A Randomized Open-Label Trial Of Ribavirin Versus ColchicineHepatology2013 | journal-articleSource:Web of Science
    • Interaction between intestinal dendritic cells and bacteria translocated from the gut in rats with cirrhosis.2012-11 | journal-article
      • PMID: 22611024
      • DOI: 10.1002/hep.25854
      Source:OSCAR PASTORviaEurope PubMed Central
    • The biological response modifier AM3 attenuates the inflammatory cell response and hepatic fibrosis in rats with biliary cirrhosis.2010-07 | journal-article
      • PMID: 20442198
      • DOI: 10.1136/gut.2008.168831
      Source:OSCAR PASTORviaEurope PubMed Central
    • Raltegravir-based highly active antiretroviral therapy has beneficial effects on the renal function of human immunodeficiency virus-infected patients after solid organ transplantation.2010-04 | journal-article
      • PMID: 20213666
      • DOI: 10.1002/lt.22005
      Source:OSCAR PASTORviaEurope PubMed Central
    • Serum lipopolysaccharide-binding protein in endotoxemic patients with inflammatory bowel disease.2007-03 | journal-article
      • PMID: 17206721
      • DOI: 10.1002/ibd.20019
      Source:OSCAR PASTORviaEurope PubMed Central
    • The extent of the collateral circulation influences the postprandial increase in portal pressure in patients with cirrhosis.2007-02 | journal-article
      • PMID: 16837532
      • PMC: PMC1856769
      • DOI: 10.1136/gut.2006.095240
      Source:OSCAR PASTORviaEurope PubMed Central
    • Hydration and Micellization Processes of n-Octyl β-d-Glucopyranoside in Aqueous Solution. A Thermodynamic and Fluorimetric Study in the Absence and Presence of SaltsLangmuir1998-05 | journal-articleSource:OSCAR PASTOR

Congresses. Posters and presentations. Thesis

ciberobn 2019
tesis lipidomica en la esclerosis múltiple jorge serna

Ongoing projects.

RELEVANCIA DE LA ACTIVIDAD DIHIDROCERAMIDA DESATURASA EN LA PROGRESIÓN DEL HÍGADO GRASO Y SU MODULACIÓN FARMACOLÓGICA.
INFLUENCE OF SEX AND SEX HORMONES ON HUMAN CHRONIC DISORDERS OF COMPLEZ ETIOLOGY (ACRONYM SEXCOMPLEX)
ESTUDIO DE LOS MECANISMOS Y TRASCENDENCIA IN VIVO DE LAS ALTERACIONES DEL TRAFICO INTRACELULAR DE LÍPIDOS INDUCIDAS POR XENOBIOTICOS Y SU PREVENCIÓN POR POLIFENOLES. 
VALIDATION OF A FAST LIPIDOMIC INDEX TO MONITOR THE INTAKE OF OMEGA-3 FATTY ACIDS IN THE BODY AND ITS APPLICATION IN NUTRITIONAL FOLLOW-UP.  

Projects of our students

Revisión del papel de las vitaminas A y E en la fibrogénesis asociada al hígado graso, María Delgado Marín et al, 2020
Desarrollo de metologías lipidómicas y su aplicación en el ámbito clínico, Silvia Recuero Del Álamo et.al, 2019
Efectos de xenobióticos en la biosíntesis de ceramidas empleando una aproximación lipidómica, Sergio Sánchez García et.al., 2018
Desarrollo y aplicación de una metodología para el seguimiento de la síntesis de esfingolípidos en cultivos celulares, Carlos Martínez Gamero et.al., 2017
Estudio del metabolismo lipídico en la Esclerosis Múltiple en un modelo animal, encefalomielitis autoinmune experimental (EAE), Belén Chaves Arquero et.al., 2014
Karla Cevallos Ibarra
Karla Cevallos Ibarra – Farmaceutica por la Universidad de Salamanca
Carlos Martínez Gamero
Carlos Martínez Gamero – Graduado en Biología por la UAH
Sergio Sánchez García
Sergio Sánchez García – Graduado en Biología por la UAH
Silvia Recuero Del Álamo
Silvia Recuero Del Álamo – Graduada en Biología Sanitaria por la UAH
Bohdan Babiy
Bohdan Babiy – Graduado en Farmacia por la UAH
maría delgado marín
María Delgado Marín – Bióloga por la UAH
Belén Chaves Arquero
Belén Chaves Arquero – Graduada en Biología Sanitaria por la UAH
Do you want to train in the field of lipidomics?

If you are interested in starting your career in the field of metabolomics, learning how to operate mass spectrometry equipment and perform lipidomics, make a stay in our laboratories as an assistant, develop your final project / master’s degree / thesis with us, do not hesitate to contact us. 

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